|
KMID : 0816119990020010109
|
|
Korean Journal of Pediatric Gastroenterolology and Nutrition
1999 Volume.2 No. 1 p.109 ~ p.115
|
|
|
A Case of Vertical Transmission of Hepatitis C Virus in an Infant of a Mother Who had Hepatitis C during Pregnancy
|
|
Oh Sang-Hyun
Moon Kyung-Rye
Park Sang-Kee
Yang Eun-Seok
Kim kuk-Hwan
|
|
|
Abstract
|
|
|
Hepatitis C virus (HCV) has been identified as an important cause of posttransfusion
hepatitis, but vertical transmission of chronic infected HCV RNA positive mothers has
been documented in some cases. The reports of the risk of perinatal infection have been
widely varied in the literature. The authors experienced one case of vertical transmission
of HCV in an infant of a mother who had hepatitis C during pregnancy. At admission,
HCV RNA (+), Ig G anti HCV (+) and Ig M anti HCV (+) were found in the mother
Also at admission, HCV RNA (+), Ig G anti HCV (+), Ig M anti HCV (+), elevation of
liver aminotransferase level and hepatosplenomegaly on ultrasonography were found in
the baby on day 31. HCV RNA (-), Ig M anti HVC (-) and normal of liver
aminotransferase level were noted on day 250 in the serum of the infant. We used
reverse transcriptase polymerase chain reaction (RT-PCR) technique to find a very small
amount of HCV RNA in the serum. All the findings suggest vertical transmission of
HCV RNA from mother to infant during 3rd trimester of pregnancy.
|
|
|
KEYWORD
|
|
|
Hepatitis C virus, Vertical transmission, Reverse transcriptase polymerase chain reaction,
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
  
|